王友彬

瘢痕和创面修复，面部年轻化，鼻部整形美容，唇裂及继发畸形修复。

1987年9月-1992年7月，泰山医学院，本科，学士，临床医学专业

1997年9月-2000年7月，潍坊医学院，研究生，硕士，整形外科专业

2000年9月-2002年7月，北京协和医学院，研究生，博士，整形外科专业

2014年1月-2014年4月，North West Embryonic Stem Cell Centre，Faculty of Life Sciences，The University of Manchester

1992年9月-1997年7月，济南铁路局临沂医院

2002年9月-2003年3月，中国医学科学院整形外科医院

2003年3月至今，北京协和医院

瘢痕和创面修复机制，面部皮肤衰老和防治。

1、“瘢痕疙瘩的手术方法改进和1033例不同部位瘢痕疙瘩的综合治疗回顾”获2016年北京协和医院医疗成果三等奖。

2、“瘢痕疙瘩的综合治疗——从基础到临床转化”获2017年北京医学科技一等奖。

3、“瘢痕疙瘩综合诊疗体现的建立——从基础研究到临床应用的转化”获2018年华夏医学科技三等奖。

4、“瘢痕疙瘩综合诊疗体现的建立——从基础研究到临床应用的转化”获2018年中华医学科学技术三等奖。

国家中医药管理局名词术语成果转化与规范推广项目评审专家

中华医学会整形外科分会瘢痕学组副组长

《牵手美容》

《整形美容随笔》

《整形美容札记》

1.Yun-Qi Liu ，Yi-Fang Liu , Xue-Mei Ma, Yi-Ding Xiao,You-Bin Wang , Ming-Zi Zhang,et al. Hydrogen-rich saline attenuates skin ischemia/reperfusion induced apoptosis via regulating Bax/Bcl-2 ratio and ASK-1/JNK pathway. Journal of Plastic, Reconstructive & Aesthetic Surgery (2015) 68, e147-e156.

2.Yi-Ding Xiao, Yun-Qi Liu, Jia-La Li,xue-Mei Ma, You-Bin Wang, et al. Hyperbaric oxygen preconditioning inhibits skin flap apoptosis in a rat ischemiaereperfusion model.Journal of Surgical Research. 199(2015), 732-739.

3.QI Zheng, GAO Chun-jin, WANG You-bin*, et al. Effects of hyperbaric oxygen preconditioning on ischemia-reperfusion infammation and skin fap survival. Chin Med J. 2013 126 (20): 3904-3909.

4.Ling ZHAO, You-bin WANG*, Shi-rui QIN, Xue-mei MA,et al. Protective effect of hydrogen-rich saline onischemia/reperfusion injury in rat skin flap. J Zhejiang Univ-Sci B (Biomed & Biotechnol). 2013；14(5):382-391.

5.ZHENG QI, WEIZHONG LIANG, YOUBIN WANG, XIAO LONG, et al. "X"-shaped incision and keloid skin-flap resurfacing: a new surgical method for auricle keloid excision and reconstruction. Dermatol Surg. 2012；38(8):1378-82.

6.Wang Youbin, Xu Jun, Wu Huanwen, Wang Xiaojun*, Wang Zhi. Recurrence of large subcutaneous keloids after tissue expansion: two case reports. J Plast Reconstr Aesthet Surg. 2013；66(2):e58-9.

7.Wang Youbin, Qi Zheng, Wang Xiaojun. Dermis Reconstruction and Dermis Fat Graft Through an Intraoral Incision: A New Method to Correct the Furrowed Philtral Column Deformity in Lesser-Form Cleft Lip.Cleft Palate Craniofac J. 2014；51(2): 3-8.

8.WENBO LI, YOUBIN WANG, XIAOJUN WANG, ZHIFEI LIU. A Keloid Edge Precut, Preradiotherapy Method in Large Keloid Skin Graft Treatment.Dermatol Surg. 2014；40(1):52-7.

9.Zhu L, Zhang M, Liu Y, Wang Y, Ma X.Necrostatin-1 Protects Against Ischemia/Reperfusion Injury by Inhibition of RIP-1 (Receptor-Interacting Protein 1) in a Rat Flap Model. Plast Reconstr Surg. 2015;136(4 Suppl):33. doi: 10.1097/01.prs.0000472315.28383.8f

10.Song K, Zhang M, Hu J, Liu Y, Liu Y, Wang Y, Ma X. Methane-rich saline attenuates ischemia/reperfusion injury of abdominal skin flaps in rats via regulating apoptosis level.BMC Surgery. 2015;15:92

11.Youbin Wang and Xiao Long. Double Layer Continuous Intradermal Sutures in Keloid Operation. J Clin Exp Dermatol Res. 2014；5:1.

12.Yi-Ding Xiao, Yun-Qi Liu, Ming-Zi Zhang, You-Bin Wang,et al. Synergistic Effect of Hyperbaric Oxygen Preconditioning and Hydrogen-rich Saline Administration in Protecting Rat Skin Flap from Ischemia/Reperfusion (I/R) Injury by Depressing Apoptosis. Plastic Aesthetic  Research. 2015；2（6）:1-7.

13.Zhang M, Xu Y, Liu Y, Cheng Y, Zhao P, Liu H, Wang Y, Ma X. Chemokine-Like Factor 1 (CKLF-1) is Overexpressed in Keloid Patients. Medicine. 2016;95(11), e3082.

14.Xiao Long, Mingzi Zhang, Yang Wang, Ru Zhao, Youbin Wang, XiaojunWang. Algorithm of chest wall keloid treatment. Medicine. 2016;95:35.

15.Ming Bai, Yifang Liu, Dechang Yin, Mingzi Zhang, Youbin Wang, Xuemei Ma, Yunqi Liu, PengxiangZhao.Inhibition of c-Jun N-terminal kinase signaling suppresses skin flap apoptosis in a rat ischemia and/or reperfusion model. Journal of Surgical Research .2016 (206) 337-346.

16.Mingzi Zhang, Kexin Song, Ning Ding, Chang Shu, Youbin Wang. Using a Distant Abdominal Skin Flap to Treat Digital Constriction Bands A Case Report for Vohwinkel Syndrome. Medicine 2016; 95(6):e2762.

17.Zhang M, Liu S, Guan E, Liu H, Dong X, Hao Y, Zhang X, Zhao P, Liu X, Pan S, Wang Y, Wang X, Liu Y. Hyperbaric oxygen therapy can ameliorate the EMT phenomenon in keloid tissue. Medicine (Baltimore). 2018 Jul;97(29):e11529. doi: 10.1097/MD.0000000000011529

18.Liu H, Song K, Zhang M, Dong X, Liu S, Wang Y. Toe keloid after nail extraction treated with surgical excision: A case report. Medicine (Baltimore). 2017 Dec;96(51):e9373. doi: 10.1097/MD.000000000000 9373.

19.Zeng A, Song K, Zhang M, Men Q, Wang Y, Zhu L, Liu Z. The "Sandwich Therapy": A Microsurgical Integrated Approach for Presternal Keloid Treatment. Ann Plast Surg. 2017 Sep;79(3):280-285. doi: 10.1097/SAP.0000000000000975.

20.Liu S, Liang W, Song K, Wang Y. Keloid Skin Flap Retention and Resurfacing in Facial Keloid Treatment. Aesthetic Plast Surg. 2018 Feb;42(1):304-309. doi: 10.1007/s00266-017-0949-1. Epub 2017 Aug 8.

21.Song KX, Liu S, Zhang MZ, Liang WZ, Liu H, Dong XH, Wang YB, Wang XJ. Hyperbaric oxygen therapy improves the effect of keloid surgery and radiotherapy by reducing the recurrence rate.J Zhejiang Univ Sci B. 2018 Nov.;19(11):853-862. doi: 10.1631/jzus.B1800132.

22.Hao Liu, Mingzi Zhang, Xinhang Dong , Yifang Liu, Yan Hao , Youbin Wang.Necrostatin-1 protects against ischemia/reperfusion injury by inhibiting receptor-interacting protein 1 in a rat flap model. Journal of Plastic, Reconstructive & Aesthetic Surgery (2018), doi: https://doi.org/10.1016/j.bjps.2018.10.019

23.Song KX, Wang YB, Zhang MZ, Wang XJ. A parasternal intercostal perforator flap for esthetic reconstruction after complete chest keloid resection: A retrospective observational cohort study.J Cosmet Dermatol. 2018 Dec;17(6):1205-1208.

24.Liu H, Zhang MZ, Liu YF, Dong XH, Hao Y, Wang YB, Necroptosis was found in a rat ischemia/reperfusion injury flap model, Chinese Medical Journal, 2019; 132: 42-50.

25.Xin-Hang Dong, Hao Liu, Ming-Zi Zhang, Peng-Xiang Zhao, Shu Liu, Yan Hao, You-Bin Wang.Postconditioning with inhaled hydrogen attenuates  skin ischemia/reperfusion injury through the  RIP-MLKL-PGAM5/Drp1 necrotic pathway. Am J Transl Res 2019;11(1):